Marbofloxacin is a synthetic, broad spectrum bactericidal agent. The bactericidal activity of marbofloxacin is concentration dependent, with susceptible bacteria cell death occurring within 20~30 minutes of exposure. Like other fluoroquinolones, marbofloxacin has demonstrated a significant post-antibiotic effect for both gram– and + bacteria and is active in both stationary and growth phases of bacterial replication.
It has good activity against many gram-negative bacilli and cocci, is effective against:
Aeromonas
Brucella
Campylobacter
Chlamydia trachomatis
Enterobacter
Escherichia coli
Haemophilus
Klebsiella spp
Mycobacterium
Mycoplasma
Proteus
Pseudomonas aeruginosa
Salmonella
Serratia
Shigella
Staphylococci (including penicillinase-producing and methicillin-resistant strains)
Vibrio
Yersinia
Marbofloxacin can be used both orally and topically. It is particularly used for infections of the skin, respiratory system and mammary glands in dogs and cats, as well as with urinary tract infections.
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