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Your Professional Pazopanib Intermediate Supplier

 

Established in 1970, Zhejiang Haizhou Pharmaceutical Co., Ltd., is a leading pharmaceutical company focusing on specialized pharmaceuticals and fine chemicals.

 

Through its three product segments - Guaiacol derivatives, Epichlorohydrin derivatives and Iodine contrast media - Haizhou Pharm offers a portfolio of products and services globally, including Active Pharmaceutical Ingredients (API), Intermediates, fine chemicals and Customs manufacturing service.

 

 
 

Why Choose Us

Complete Product Qualifications

Haizhou Pharm has obtained certifications for ISO 9001, ISO 14001, and OHSAS 18001. The ISO and OHSAS management philosophy is deeply integrated into every stage of the company’s operations.

Quality Control

The API production at Haizhou Pharm complies with the cGMP standard and has been officially approved by regulatory authorities such as the National Medical Products Administration (NMPA, formerly China FDA), the U.S. Food and Drug Administration (US-FDA), and the European Directorate for the Quality of Medicines & HealthCare (EDQM).

A Global Supply Chain

The company exports its products to numerous countries and regions worldwide, having established a comprehensive sales network and customer service system.

 

 

Parameter

Intermediate

2,3-Dimethyl-2H-indazol-6-amine

Main Application

Pazopanib

CAS NO

444731-72-0

Availability

By order

 

Types of Pazopanib Intermediate

 

The pazopanib intermediate produced by our company mainly include the following types:

2,3-dimethyl-2H-indazol-6-amine

2,3-dimethyl-2H-indazol-6-amine

 

2,3-dimethyl-2H-indazol-6-amine hydrochloride is a pharmaceutical intermediate that serves as a key component in the synthesis of pazopanib. Additionally, it may also manifest as an impurity in pazopanib hydrochloride during the manufacturing process.

2,3-dimethyl-2H-indazol-6-amine Hydrochloride

2,3-dimethyl-2H-indazol-6-amine Hydrochloride

2,3-dimethyl-2H-indazol-6-amine hydrochloride is a pharmaceutical intermediate that serves as an impurity associated with the production of pazopanib hydrochloride.

2,3-dimethyl-6-nitro-2H-indazole

2,3-dimethyl-6-nitro-2H-indazole

 

2,3-Dimethyl-6-nitro-2H-indazole is a heterocyclic compound with the molecular formula C9H9N3O2. According to SEQENS, it serves as an intermediate in the synthesis of the drug Pazopanib.

 

Nature

Melting point

>230°C (dec.)

Storage temp

Inert atmosphere,Room Temperature

Solubility

DMSO (Slightly), Methanol (Slightly)

Form

Solid

Color

Pale Beige to Light Beige

Stability:

Hygroscopic

Uses

2,3-Dimethyl-6-amino-2H-indazole is an impurity in the synthesis of Pazopanib (P210925) hydrochloride, an oral angiogenesis inhibitor targeting VEGFR and PDGFR.

 

Delivery Information
 
 

Shipping Methods

We offer a variety of shipping options, including sea freight, railway transportation, and international express delivery, to meet the diverse needs of our customers.

 
 
 

Estimated Delivery Time

We will provide you with the estimated delivery time for your order, which will be clearly stated in the formal order to ensure your rights are protected, allowing you to arrange for the receipt of your goods in a timely manner.

 
 
 

Order Tracking

We provide order tracking services, allowing you to stay informed about the current status and expected arrival time of your order. Detailed inspection information and shipping manifests, including photos and videos, are provided to ensure the security of your transactions.

 

 

 

FAQ

 

Q: What are the precautions for pazopanib?

A: Check with your doctor or pharmacist before you start or stop taking any other drugs. Avoid grapefruit and grapefruit juice for the duration of your treatment, as these may interact with pazopanib. The drinking of alcohol (in small amounts) does not appear to affect the safety or usefulness of pazopanib.

Q: What are the guidelines for pazopanib?

A: Pazopanib should be taken on an empty stomach, at least one hour before or two hours after a meal. Tablets should be taken whole with water and not broken or crushed. If a dose is missed or the patient vomits after taking their dose, the patient should not be given an additional dose.

Q: How long can you stay on pazopanib?

A: You will usually carry on taking pazopanib for as long as it is working for you. Do not stop taking pazopanib without talking to your doctor first. If you have certain side effects, or changes in your blood test results, your doctor may tell you to stop taking pazopanib for a short time or to reduce the dose you take.

Q: What drugs interact with pazopanib?

A: Some products that may interact with this drug include: irinotecan, other drugs that can cause bleeding/bruising (including antiplatelet drugs such as clopidogrel, NSAIDs such as ibuprofen, "blood thinners" such as warfarin). Aspirin can increase the risk of bleeding when used with this medication.

Q: What is the response rate for pazopanib?

A: The clinical response rate was 46.3%. Patients with hemangioendothelioma and alveolar soft part sarcoma exhibited an improved response to treatment compared with that of patients with other subtypes. Line of therapy and tumor grade were not significantly associated with progression-free survival or clinical response.

We're professional pazopanib intermediate manufacturers and suppliers in China, specialized in supplying high quality products and service. We warmly welcome you to buy high-grade pazopanib intermediate at competitive price from our factory.

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